A 14-year-old girl has sustained serious burns after a fire engulfed a Laidley home this morning.

Emergency Services attended the house fire on Cooper Street just after 10am.

A Queensland Ambulance spokesperson said there were two occupants in the house at the time of the blaze.

The girl is currently in a critical condition after suffering extensive burns.

He said she was initially transported to Laidley Hospital before being airlifted to the Royal Children's Hospital by a Rescue 500 helicopter and was taken into surgery.

A 49-year-old woman was also taken to Ipswich General Hospital with smoke inhalation.

Queensland Fire and Rescue Lockyer and Somerset Acting Area Commander Tyson Loetzsch said crews from Laidley, Rosewood and Gatton attended the scene.

He said further investigations by the Fire and Investigation Unit and police would determine the cause and origin of the fire.