Common antibiotics linked to miscarriage in early pregnancy

A NEW study published in the Canadian Medical Association Journal (CMAJ) has found a link between antibiotic use in early pregnancy and miscarriage.

Researchers found that common antibiotics, such as macrolides, quinolones, tetracyclines, sulfonamides and metronidazole contributed to the risk.

Thankfully, two types of antibiotic commonly used to treat urinary tract infections in pregnant women (erythromycin and nitrofurantoin) were NOT associated with increased risk.

Dr. Anick Bérard from Université de Montréal in Quebec says that infections are prevalent during pregnancy.

"Although antibiotic use to treat infections has been linked to a decreased risk of prematurity and low birth weight in other studies, our investigation shows that certain types of antibiotics are increasing the risk of spontaneous abortion, with a 60% to two-fold increased risk," Bérard said.

"Given that the baseline risk of spontaneous abortion can go as high as 30%, this is significant."

The review involved 95,000 women. 8702 cases, defined as clinically detected spontaneous abortions, were matched with 87 020 controls. A total of 1428 (16.4%) cases were exposed to antibiotics during early pregnancy.

"The main risk this research throws up is for those women who don't know they are pregnant," former trustee of The Miscarriage Association, Dr Nicola Davies, told the Telegraph.

"Most of these drugs are drugs you wouldn't prescribe if you knew a woman was pregnant."

The antibiotics used to treat respiratory infections, some intestinal infections and skin infections, are usually from the macrolide family.

Macrolides are also regularly used for those resistant to penicillin.

The antibiotics used to treat chronic acne are often from the tetracycline family.

So, if you suspect you may be pregnant, make sure you tell your GP before getting your prescription.

This article originally appeared on Kidspot and has been republished here with permission.

News Corp Australia

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